I will say this: It was a JAM PACKED theater. Really crowded. When my son's old school had its talent show around four years ago, I think twenty people showed up.
The most entertaining part for me was the sit-down comic who might have given ribit a run for his money. He calls himself "Pegasus." Could be the next Henny Youngman for all we know. He was THAT good. I have no idea why he's dressed up as a marshmallow. http://youtu.be/Qwu5MBUKmwI
What, though, of the student who took second place - who essentially won this talent show of HIGH SCHOOLERS? You must see it to believe it. My take is that if EVER there was a gal in desperate need of being bent over Daddy's knee while he tans her hide, this is the one. He should have done it about five years ago, though. Now, she's just another screwed up chick - but that's only my take. Your mileage may vary. http://youtu.be/F-j8fNNzd04
Walter Williams is an American ICON and should, like Thomas Sowell, be accorded their rightful respected places in American Scholar circles...
Here is where I and Dr. Williams disagree.
The MONEY that was FORCEFULLY and without MY CONSENT STOLEN from my paycheck for whatever purposes, regardless of those purposes, was still MY MONEY. I earned it.\
It was taken from me without my consent or approval. I had NO SAY in that matter and yet, it came from MY EARNINGS.
Hence it belonged to me and theoretically still does.
I am not duped. I am not ignorant. I know FDR played a PONZI scheme on America and many were thinking to themselves that they will benefit from the backs of others, free money syndrome....
Yes, Social Security is a massive PONZI Scheme Bernie Madoff can only dream about...
That does not mean I am blind to it or agree with it.
What does Dr. WIlliams suggest I as a citizen do about it?? Beside call me names and describe me as "duped"?
He is right until the very end....
GOT a solution that works out for us I would love to hear it Dr. Williams????
It IS MY MONEY. I should be able to tell you to the DIME how much of my money was taken from me without my consent and used for whatever purpose the Federal government wanted to use it for. We allknow the criminal politicians stole it and used it to pay for their over spending and sticking our noses every where in the world we did not belong. Or giving it away like they earned it, to every nation on earth... and redistributing it to anyone and everyone they thought needed it.....
Question for all?
Did Dr. Williams and Jefferson and Madison also mean that tax money should NOT be used to send to help States out with nature's calamities and that States should take care of those issues on their own level???
I am a bit unclear on that.....
Anyway, I find it a bit offensive that Dr. Williams has ascribed willful ignorance (duped) to most of us regarding the theft by government, started by FDR (DEMOCRAT LIBERAL), of money from our earnings for redistribution known as social security AND that the money was not really ours....
Msg. 47199 of 47202 (This msg. is a reply to
05163 by
capt_nemo)
Jump:
LOL a recap post. GO TRUMP!!!!!!!!!!!!!!!!!!!!!!!!!!!
Realist - Everybody in America is soft, and hates conflict. The cure for this, both in politics and social life, is the same -- hardihood. Give them raw truth.
- - - - - The above is a reply to the following message:
Ted Nugent Posted This On Facebook About Donald Trump. Priceless!
By: capt_nemo in
POPE IV Thu, 31 Mar 16 10:54 AM
At this time I do not endorse Donald Trump anymore than I endorse Ted Cruz as I admire both gentlemen. But these points are SO damn special!
Obama is against Trump
The Media is against Trump
The establishment Democrats are against Trump
The establishment Republicans are against Trump
The Pope is against Trump
The UN is against Trump
The EU is against Trump
China is against Trump
Mexico is against Trump
Soros is against Trump
Black Lives Matter is against Trump
MoveOn.Org is against Trump
Koch Bro's are against Trump
Hateful, racist, violent Liberals are against Trump
Bonus points
Cher says she will leave the country
Mylie Cyrus says she will leave the country
Whoopi says she will leave the country
Rosie says she will leave the country
Al Sharpton says he will leave the country
Gov. Brown says California will build a wall
The Food and Drug Administration’s out-of-the-blue approval of Sarepta Therapeutics’ second Duchenne muscular dystrophy (DMD) drug sent the company’s stock soaring on Friday.
Shares of Sarepta SRPT, +35.92% jumped 35% in morning trading after Thursday evening’s Vyondys 53 approval.
DMD is a rare disorder that mainly affects male children. About 8% of the children who have DMD have the gene mutation that Vyondys 53 treats.
The “Vyondys 53 approval removes a major overhang for the stock as concerns surrounding the future SRPT’s commercial products such as Exondys 51 being pulled from the market and cash flows required to support SRPT’s growing gene therapy platforms have now been lifted,” SVP Leerink’s Joseph Schwartz wrote on Dec. 12.
Sarepta already markets Exondys 51, which was the first FDA-approved DMD treatment in 2016. And until now, it has been the company’s only commercialized therapy, bringing in $99 million in sales in the third quarter, up from $78 million in the same period a year ago.
Until Aug. 19, when the regulator sent a complete response letter to the company citing a pair of risk concerns about the then experimental therapy, it was expected that Vyondys 53 would follow the same accelerated pathway as Exondys 51. The company’s stock tumbled 18% to $120.31 that day and has since failed to recover to its year-to-date high of $156.91 on July 15. The stock closed Thursday at $100.47. Company officials said they were surprised by the letter at that time.
“In the span of four months, we commenced and completed the formal dispute resolution process culminating in the grant of our appeal, resubmitted our [new drug application] and obtained an approval–a great benefit to DMD patients awaiting treatment,” Sarepta president and CEO Doug Ingram said in a news release.
A Sarepta spokeswoman said Exondys51 and Vyondys53 both have an annual list price of approximately $300,000. However, pharmacy benefit manager Prime Therapeutics told The New York Times in 2017 that the price can sometimes reach $750,000 per patient, in part because it is weight-based.
That price tag has raised questions among experts even though there are limited treatment options for DMD patients. The Institute for Clinical and Economic Review, a watchdog that conducts comparative clinical effectiveness research, said in August that most insurers have responded to the high price of Exondys 51 by narrowing coverage. “Three years after approval, the manufacturer has provided no high-quality evidence of benefit, many patients and families are surely losing out, and only the manufacturer truly benefits from this deplorable situation,” ICER chief medical officer David Rind said in a statement then.
Sarepta is also developing casimersen, another experimental DMD treatment that is expected to receive an FDA decision in the first half of next year. But not all analysts believe that the approval of Vyondys 53 bodes well for the FDA’s take on casimersen and other DMD medications in the industry pipeline.
“While the approval of [Vyondys 53] provides some alleviation to the P&L’s operational burn, we remain cautious of the next steps for development both for the PMO and gene therapy franchise,” wrote Oppenheimer analyst Hartaj Singh.
Investors are less cautious. Shares of Wave Life Sciences WVE, +2.67%, which is developing a DMD treatment, are up 6%. Audentes Therapeutics BOLD, +0.04%, which Astellas Pharma announced last week that it planned to buy for $3 billion, is also working on a DMD drug. Its stock was flat.
Sarepta’s stock has gained 25% year-to-date, while the S&P 500 SPX, +0.06% is up about 26%.
I believe this is from the Californica wildfires . . .
What bothers me, is that ALL the houses are burnt
down, but many trees, grass, and one shed are
not burnt out.
I'm guessing that the houses were all built of stuff that
burns quick and easy . . . while the trees must have some
natural resistance to fire? And I have to wonder what
that shed was made of.
Msg. 47194 of 47202 (This msg. is a reply to
47193 by
DGpeddler)
Jump:
Same to you bro!!!!!!!!!!!!!!! so far so good here,,,,,,,,,,,,,,
Realist - Everybody in America is soft, and hates conflict. The cure for this, both in politics and social life, is the same -- hardihood. Give them raw truth.
- - - - - The above is a reply to the following message:
Happy Fourth of July
By: DGpeddler in
POPE IV Tue, 03 Jul 18 8:26 PM
Msg. 47192 of 47202 (This msg. is a reply to
47191 by
DGpeddler)
Jump:
What percent of Christians identify themselves as liberal and what percent as conservative?
Jonathan Andersen, United Methodist Pastor
Answered Aug 9 2011
A percentage would be impossible to calculate. However, as Christianity continues to grow in the Majority World it is largely in forms of evangelicalism and is trending towards theological conservatism.
Realist - Everybody in America is soft, and hates conflict. The cure for this, both in politics and social life, is the same -- hardihood. Give them raw truth.
- - - - - The above is a reply to the following message:
Msg. 47188 of 47202 (This msg. is a reply to
47187 by
Zimbler0)
Jump:
Roger that zimmer. WE RULE!!!!!!!!!!!!!!!!!!!
Realist - Everybody in America is soft, and hates conflict. The cure for this, both in politics and social life, is the same -- hardihood. Give them raw truth.
DON'T BELIEVE A DAMN WORD YOU READ ON THIS WEBSITE!
The reader is responsible for discerning the validity, factuality or implications of information posted here, be it fictional or based on real events. Moderators on this forum make every effort to review the material posted on this site however, it is not realistically possible for a one man team to manually review each and every one of the posts atomicbobs.com gets on a daily basis.
The content of posts on this site, including but not limited to links to other web sites, are the expressed opinion of the original poster and are in no way representative of or endorsed by the owners or administration of this website. The posts on this website are the opinion of the specific author and are not statements of advice, opinion, or factual information on behalf of the owner or administration of Atomicbobs. This site may contain adult language, if you feel you might be offended by such content, you should log off immediately.
Not all posts on this website are intended as truthful or factual assertion by their authors. Some users of this website are participating in internet role playing, with or without the use of an avatar. NO post on this website should be considered factual information on face value alone. Users are encouraged to
USE DISCERNMENT
and do their own follow up research while reading and posting on this website. Atomicbobs.com reserves the right to make changes to, corrections and/or remove entirely at any time posts made on this website without notice. In addition, Atomicbobs.com disclaims any and all liability for damages incurred directly or indirectly as a result of a post on this website.
This website implements certain security features in order to prevent spam and posting abuse. By making a post on this website you consent to any automated security checks required by our system to authenticate your IP address as belonging to an actual human. It is forbidden to make posts on this website from open proxy servers. By making a post on this website you consent to an automated one time limited port scan of your IP address which is required by our security system to validate the authenticity of your internet connection.
This site is provided "as is" without warranty of any kind, either expressed or implied. You should not assume that this site is error-free or that it will be suitable for the particular purpose which you have in mind when using it. In no event shall Atomicbobs.com be liable for any special, incidental, indirect or consequential damages of any kind, or any damages whatsoever, including, without limitation, those resulting from loss of use, data or profits, whether or not advised of the possibility of damage, and on any theory of liability, arising out of or in connection with the use or performance of this site or other documents which are referenced by or linked to this site.
Some events depicted in certain posting and threads on this website may be fictitious and any similarity to any person living or dead is merely coincidental. Some other articles may be based on actual events but which in certain cases incidents, characters and timelines have been changed for dramatic purposes. Certain characters may be composites, or entirely fictitious.
We do not discriminate against the mentally ill!
Fair Use Notice:
This site may contain copyrighted material the use of which has not always been specifically authorized by the copyright owner. Users may make such material available in an effort to advance awareness and understanding of issues relating to civil rights, economics, individual rights, international affairs, liberty, science & technology, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law.
At some point freedom of speech and copyright law merge. The following interpretation of "Fair Use" and subsequent posting policy were developed with the assistance of qualified legal council however, we are not lawyers and cannot offer you legal advise as to the limits of "Fair Use"
In accordance with industry accepted best practices we ask that users limit their copy / paste of copyrighted material to the relevant portions of the article you wish to discuss and no more than 50% of the source material, provide a link back to the original article and provide your original comments / criticism in your post with the article.
Though legally each situation is evaluated independently according to guidelines that were intentionally left open to interpretation, we believe generally this policy represents "Fair Use" of any such copyrighted material for the purposes of education and discussion.
You are responsible for what you "publish" on the internet. You must be sure any copyrighted material you choose to post for discussion on this forum falls within the limits of "Fair Use" as defined by the law.
If you are a legal copyright holder or a designated agent for such and you believe a post on this website falls outside the boundaries of "Fair Use" and legitimately infringes on yours or your clients copyright
we may be contacted concerning copyright matters at:
If you require a courier address please send a fax or email and we will provide you with the required information.
For expedited human review & removal of potential copyright violations we encourage users & copyright holders to utilize the "Report Copyright Violation" button that accompanies each post published on this website.
In accordance with section 512 of the U.S. Copyright Act our contact information has been registered with the United States Copyright Office. "Safe Harbor" noticing procedures as outlined in the DMCA apply to this website concerning all 3rd party posts published herein.
If notice is given of an alleged copyright violation we will act expeditiously to remove or disable access to the material(s) in question. It is our strict policy to disable access to accounts of repeat copyright violators. We will also ban the IP address of repeat offenders from future posting on this website with or without a registered account.
All 3rd party material posted on this website is copyright the respective owners / authors. Atomicbobs.com makes no claim of copyright on such material.
Please be aware any communications sent complaining about a post on this website may be posted publicly at the discretion of the administration.
---
DON'T BREAK THE LAW!
---
Other than that you can do / say whatever you want on this forum.
We reserve the right to block access to this website by any individual or organization at any time for any reason whatsoever or no reason at all.
| 
