The NIH's "Genome TV" youtube channel (which one can mark or subscribe to) is where this came from, there are any number of other seminars that are similarly mind boggling. Given that one can bang out a genome for a remarkably small amount of money, the databse of e.g. rare disease, metagenomes, and comparative genomics is staggering.
Metagenomics is only the latest thingy, the applications of it are only limited by imagination.