Hi clo,
I don't take the US Chamber of Commerce too seriously. It's a right wing organization. They will create the appearance that all business leaders agree with them. But rather like the NRA, its membership is self-selecting.
Fact is, O inherited the right wing's mess. He has done enough to clean most of it up (at least the freefall has been stopped and unemployment is gradually shrinking). I think the Rs really hoped to get the credit for O's work under a Romney administration. But instead, as the economy recovers, they look more and more likely to appear as wrong as they always have been about how the economy works. And the Democrats will receive the credit they richly deserve.
A second Obama term shifts the US away from the right wing certainties and back towards the middle. This will produce a more civilised society. It is about time. The USA should not be held hostage by its zealots.