Diabetes May Be Reversed by Long-Used Vaccine for TB
By Shannon Pettypiece - Aug 9, 2012 12:01 AM ET
Bloomberg.com
A tuberculosis vaccine in use for 90 years may help reverse Type 1 diabetes and eliminate the life- long need for insulin injections, say Harvard University researchers raising money to conduct large, human studies.
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In the study, researchers administered two doses of the BCG vaccine to three patients who had been diagnosed with Type 1 diabetes. The patients were followed for 20 weeks and two of the three were found to have an increase in the death of the insulin-harming cells and a rise in elevation in C-peptide levels, suggesting the production of insulin.
“These patients have been told their pancreases were dead,” Faustman said. “We can take those people, give them a very low dose twice and see their pancreases kick in and start to make small amounts of insulin.”
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So now, she is trying to raise money to pay for the expensive larger human trials. Her lab so far has received $11 million of the $25 million needed to pay for the next stage of testing. All of the money is coming from private donors, the largest of which is the Iacocca Family Foundation.
More: http://www.bloomberg.com/news/2012-08-08/diabetes-may-be-reversed-by-long-used-vaccine-for-tb.html
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